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Placebo Fraud: 72% of Clinical Trials of injectable drug placebos not defined

October 30, 2010 by Good Samaritan

Drug brainwashed people benefiting monetarily from this drug industry are poo pooing the results of this study.  Saying that this is too sensationalist.  No it’s not. Not defining your control / placebo is basic grade school science!

This is not sensationalist this is just fact from a study that came out:

92% of pill clinical trials do not disclose the contents of the placebo they use!

and

73% of injectible clinical trials do not disclose the contents of the injectible placebo they use!

This DE FACTO invalidates all those so called clinical trials as they do not define the control placebo.

Shame on the entire industry.

The public should wisen up.

Are you taking maintenance drugs?

Did you know the clinical trials of your drugs are now invalidated?

If you are a doctor in practice, in your own conscience, can you just carry on prescribing the same stuff now that you know the clinical trials backing those drug claims are all false?

Come on, this rocks the very foundation of the drug industry!

Ah, it will only hit home when drug company stock prices take a beating. My fearless forecast is this study will be shelved and be forgotten.

What’s in Placebos: Who Knows? Analysis of Randomized, Controlled Trials

1. Beatrice A. Golomb, MD, PhD;
2. Laura C. Erickson, BS;
3. Sabrina Koperski, BS;
4. Deanna Sack, BS;
5. Murray Enkin, MD; and
6. Jeremy Howick, PhD

1. From the University of California, San Diego, School of Medicine, San Diego, California; McMaster University, Hamilton, Ontario, Canada; and Centre for Evidence-Based Medicine, University of Oxford, Oxford, United Kingdom.

Abstract

Background: No regulations govern placebo composition. The composition of placebos can influence trial outcomes and merits reporting.

Purpose: To assess how often investigators specify the composition of placebos in randomized, placebo-controlled trials.

Data Sources: 4 English-language general and internal medicine journals with high impact factors.

Study Selection: 3 reviewers screened titles and abstracts of the journals to identify randomized, placebo-controlled trials published from January 2008 to December 2009.

Data Extraction: Reviewers independently abstracted data from the introduction and methods sections of identified articles, recording treatment type (pill, injection, or other) and whether placebo composition was stated. Discrepancies were resolved by consensus.

Data Synthesis: Most studies did not disclose the composition of the study placebo. Disclosure was less common for pills than for injections and other treatments (8.2% vs. 26.7%; P = 0.002).

Limitation: Journals with high impact factors may not be representative.

Conclusion: Placebos were seldom described in randomized, controlled trials of pills or capsules. Because the nature of the placebo can influence trial outcomes, placebo formulation should be disclosed in reports of placebo-controlled trials.

From: http://www.annals.org/content/153/8/532.abstract

Filed Under: Diseases, General Health

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